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Literature summary extracted from
- The effect of kiwifruit (Actinidia deliciosa) cysteine protease actinidin on the occludin tight junction network in T84 intestinal epithelial cells (2014), Food Chem. Toxicol., 72, 61-68.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.22.14 | Actinidia deliciosa | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.22.14 | casein + H2O | - |
Actinidia deliciosa | ? | - |
? |  |
| 3.4.22.14 | occludin + H2O | - |
Actinidia deliciosa | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.22.14 | actinidin | - |
Actinidia deliciosa |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 3.4.22.14 | physiological function | actinidin disrupts the epithelial barrier function of human intestinal T84 cells by degrading the tight junction protein occludin. Exposure of T84 cells to biologically active actinidin significantly decreases the transepithelial resistance across the intestinal epithelial monolayers | Actinidia deliciosa |
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Release 2023.1 (January 2023)
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